siRNA, Anti-HIRA, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21780WQ-2OMe)

The product SIRGT21780WQ-2OMe is a type of small interfering RNA (siRNA) that targets HIRA gene and regulates the expression of gene. The siRNA interferes with the expression of HIRA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003325.3
Alternative Names DGCR1; TUP1; TUPLE1
Related Diseases DiGeorge syndrome
Purification HPLC
Target Gene
Gene ID 7290
Uniprot ID P54198
Sub Cat Target Species Modification Scale  
SIRGT22780WQ-2F HIRA Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23780WQ-2MOE HIRA Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24780WQ-LNA HIRA Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21780WQ-RB HIRA Human Ribo-modified Inquiry
SIRGT22780WQ-BB HIRA Human Backbone-modified Inquiry

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