siRNA, Anti-HIST1H1A, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT06976WQ-2OMe)

The product SIRGT06976WQ-2OMe is a type of small interfering RNA (siRNA) that targets HIST1H1A gene and regulates the expression of gene. The siRNA interferes with the expression of HIST1H1A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005325.3
Alternative Names H1.1; H1A; H1F1; HIST1
Related Diseases Retinitis Pigmentosa
Purification HPLC
Target Gene
Gene ID 3024
Uniprot ID Q02539
Sub Cat Target Species Modification Scale  
SIRGT07976WQ-2F HIST1H1A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08976WQ-2MOE HIST1H1A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT06976WQ-RB HIST1H1A Human Ribo-modified Inquiry
SIRGT07976WQ-BB HIST1H1A Human Backbone-modified Inquiry

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