siRNA, Anti-HIST1H2AE, 2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT08968WQ-2MOE)
The product SIRGT08968WQ-2MOE is a type of small interfering RNA (siRNA) that targets HIST1H2AE gene and regulates the expression of gene. The siRNA interferes with the expression of HIST1H2AE gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_021052.2 |
| Alternative Names | H2A.1; H2A.2; H2A/a; H2AFA |
| Related Diseases | Fanconi Anemia |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT09968WQ-LNA | HIST1H2AE | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT06968WQ-RB | HIST1H2AE | Human | Ribo-modified | ||
| SIRGT07968WQ-BB | HIST1H2AE | Human | Backbone-modified |