siRNA, Anti-HIST1H2BJ, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT26693WQ-2OMe)

The product SIRGT26693WQ-2OMe is a type of small interfering RNA (siRNA) that targets HIST1H2BJ gene and regulates the expression of gene. The siRNA interferes with the expression of HIST1H2BJ gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_021058.3
Alternative Names H2B/r; H2BFR; H2BJ
Related Diseases Metabolism of proteins
Purification HPLC
Target Gene
Gene ID 8970
Uniprot ID P06899
Sub Cat Target Species Modification Scale  
SIRGT27693WQ-2F HIST1H2BJ Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28693WQ-2MOE HIST1H2BJ Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT26693WQ-RB HIST1H2BJ Human Ribo-modified Inquiry
SIRGT27693WQ-BB HIST1H2BJ Human Backbone-modified Inquiry

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