siRNA, Anti-HIST1H3A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26252WQ-2OMe)

The product SIRGT26252WQ-2OMe is a type of small interfering RNA (siRNA) that targets HIST1H3A gene and regulates the expression of gene. The siRNA interferes with the expression of HIST1H3A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003529.2
Alternative Names H3/A; H3FA
Related Diseases Diffuse Intrinsic Pontine Glioma
Purification HPLC
Target Gene
Gene ID 8350
Uniprot ID P68431
Sub Cat Target Species Modification Scale  
SIRGT27252WQ-2F HIST1H3A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28252WQ-2MOE HIST1H3A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29252WQ-LNA HIST1H3A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26252WQ-RB HIST1H3A Human Ribo-modified Inquiry
SIRGT27252WQ-BB HIST1H3A Human Backbone-modified Inquiry

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