siRNA, Anti-HIST1H3E, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26255WQ-2OMe)

The product SIRGT26255WQ-2OMe is a type of small interfering RNA (siRNA) that targets HIST1H3E gene and regulates the expression of gene. The siRNA interferes with the expression of HIST1H3E gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003532.2
Alternative Names H3.1; H3/d; H3FD
Related Diseases Brain Stem Glioma
Purification HPLC
Target Gene
Gene ID 8353
Uniprot ID P68431
Sub Cat Target Species Modification Scale  
SIRGT27255WQ-2F HIST1H3E Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28255WQ-2MOE HIST1H3E Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29255WQ-LNA HIST1H3E Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26255WQ-RB HIST1H3E Human Ribo-modified Inquiry
SIRGT27255WQ-BB HIST1H3E Human Backbone-modified Inquiry

Related Products