siRNA, Anti-HIST1H3F, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT26691WQ-2OMe)

The product SIRGT26691WQ-2OMe is a type of small interfering RNA (siRNA) that targets HIST1H3F gene and regulates the expression of gene. The siRNA interferes with the expression of HIST1H3F gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_021018.2
Alternative Names H3/i; H3FI
Related Diseases Adult Infiltrating Astrocytic Neoplasm
Purification HPLC
Target Gene
Gene ID 8968
Uniprot ID P68431
Sub Cat Target Species Modification Scale  
SIRGT27691WQ-2F HIST1H3F Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT29691WQ-LNA HIST1H3F Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26691WQ-RB HIST1H3F Human Ribo-modified Inquiry
SIRGT27691WQ-BB HIST1H3F Human Backbone-modified Inquiry

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