siRNA, Anti-HIST1H3H, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26259WQ-2OMe)

The product SIRGT26259WQ-2OMe is a type of small interfering RNA (siRNA) that targets HIST1H3H gene and regulates the expression of gene. The siRNA interferes with the expression of HIST1H3H gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003536.2
Alternative Names H3/k; H3F1K; H3FK
Related Diseases Adult Infiltrating Astrocytic Neoplasm
Purification HPLC
Target Gene
Gene ID 8357
Uniprot ID P68431
Sub Cat Target Species Modification Scale  
SIRGT27259WQ-2F HIST1H3H Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28259WQ-2MOE HIST1H3H Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29259WQ-LNA HIST1H3H Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26259WQ-RB HIST1H3H Human Ribo-modified Inquiry
SIRGT27259WQ-BB HIST1H3H Human Backbone-modified Inquiry

Related Products