siRNA, Anti-HIST1H4C, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26264WQ-2OMe)

The product SIRGT26264WQ-2OMe is a type of small interfering RNA (siRNA) that targets HIST1H4C gene and regulates the expression of gene. The siRNA interferes with the expression of HIST1H4C gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003542.3
Alternative Names H4/g; H4FG; dJ221C16.1
Related Diseases Hyperinsulinemic Hypoglycemia, Familial
Purification HPLC
Target Gene
Gene ID 8364
Uniprot ID P62805
Sub Cat Target Species Modification Scale  
SIRGT27264WQ-2F HIST1H4C Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28264WQ-2MOE HIST1H4C Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29264WQ-LNA HIST1H4C Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26264WQ-RB HIST1H4C Human Ribo-modified Inquiry
SIRGT27264WQ-BB HIST1H4C Human Backbone-modified Inquiry

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