siRNA, Anti-HIST1H4G, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26269WQ-2OMe)

The product SIRGT26269WQ-2OMe is a type of small interfering RNA (siRNA) that targets HIST1H4G gene and regulates the expression of gene. The siRNA interferes with the expression of HIST1H4G gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003547.2
Alternative Names H4/l; H4FL
Related Diseases PKMTs methylate histone lysines
Purification HPLC
Target Gene
Gene ID 8369
Uniprot ID Q99525
Sub Cat Target Species Modification Scale  
SIRGT27269WQ-2F HIST1H4G Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28269WQ-2MOE HIST1H4G Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29269WQ-LNA HIST1H4G Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26269WQ-RB HIST1H4G Human Ribo-modified Inquiry
SIRGT27269WQ-BB HIST1H4G Human Backbone-modified Inquiry

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