siRNA, Anti-HIST3H3, 2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT26210WQ-2OMe)

The product SIRGT26210WQ-2OMe is a type of small interfering RNA (siRNA) that targets HIST3H3 gene and regulates the expression of gene. The siRNA interferes with the expression of HIST3H3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003493.2
Alternative Names H3.4; H3/g; H3FT; H3t
Related Diseases Colon Leiomyoma
Purification HPLC
Target Gene
Gene ID 8290
Uniprot ID Q16695
Sub Cat Target Species Modification Scale  
SIRGT28210WQ-2MOE HIST3H3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT26210WQ-RB HIST3H3 Human Ribo-modified Inquiry
SIRGT27210WQ-BB HIST3H3 Human Backbone-modified Inquiry

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