siRNA, Anti-HLA-DQA2, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT11041WQ-2OMe)

The product SIRGT11041WQ-2OMe is a type of small interfering RNA (siRNA) that targets HLA-DQA2 gene and regulates the expression of gene. The siRNA interferes with the expression of HLA-DQA2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_020056.4
Alternative Names DX-ALPHA; HLA-DXA; HLADQA2
Related Diseases Podoconiosis, Rheumatoid Arthritis
Purification HPLC
Target Gene
Gene ID 3118
Uniprot ID P01906
Sub Cat Target Species Modification Scale  
SIRGT12041WQ-2F HLA-DQA2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT14041WQ-LNA HLA-DQA2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11041WQ-RB HLA-DQA2 Human Ribo-modified Inquiry
SIRGT12041WQ-BB HLA-DQA2 Human Backbone-modified Inquiry

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