siRNA, Anti-HLA-G, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11049WQ-2OMe)

The product SIRGT11049WQ-2OMe is a type of small interfering RNA (siRNA) that targets HLA-G gene and regulates the expression of gene. The siRNA interferes with the expression of HLA-G gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.