siRNA, Anti-HLA-DOA, 2'-MOE-modified(CAT#: SIRGT13037WQ-2MOE)
The product SIRGT13037WQ-2MOE is a type of small interfering RNA (siRNA) that targets HLA-DOA gene and regulates the expression of gene. The siRNA interferes with the expression of HLA-DOA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| Modification | 2'-O-methoxyethyl (2'-MOE) |
| Scale | 20/50/100/200 nmole |
| NCBI RefSeq | NM_002119.3 |
| Alternative Names | HLA-DNA; HLA-DZA; HLADZ |
| Related Diseases | Keshan Disease, Hirata Disease |
| Purification | HPLC |