siRNA, Anti-HLA-DRA, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11042WQ-2OMe)

The product SIRGT11042WQ-2OMe is a type of small interfering RNA (siRNA) that targets HLA-DRA gene and regulates the expression of gene. The siRNA interferes with the expression of HLA-DRA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_019111.4
Alternative Names HLA-DRA1
Related Diseases Graham-Little-Piccardi-Lassueur Syndrome, Heart Lymphoma
Purification HPLC
Target Gene
Gene ID 3122
Uniprot ID P01903
Sub Cat Target Species Modification Scale  
SIRGT12042WQ-2F HLA-DRA Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13042WQ-2MOE HLA-DRA Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14042WQ-LNA HLA-DRA Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11042WQ-RB HLA-DRA Human Ribo-modified Inquiry
SIRGT12042WQ-BB HLA-DRA Human Backbone-modified Inquiry

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