siRNA, Anti-HMGXB4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31494WQ-2OMe)

The product SIRGT31494WQ-2OMe is a type of small interfering RNA (siRNA) that targets HMGXB4 gene and regulates the expression of gene. The siRNA interferes with the expression of HMGXB4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001003681.2
Alternative Names HMG2L1; HMGBCG; THC211630
Related Diseases Chromatin binding
Purification HPLC
Target Gene
Gene ID 10042
Uniprot ID Q9UGU5
Sub Cat Target Species Modification Scale  
SIRGT32494WQ-2F HMGXB4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33494WQ-2MOE HMGXB4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34494WQ-LNA HMGXB4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31494WQ-RB HMGXB4 Human Ribo-modified Inquiry
SIRGT32494WQ-BB HMGXB4 Human Backbone-modified Inquiry

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