siRNA, Anti-HSD17B8, 2'-F/2'-OMe/2'-MOE/LNA-modified(CAT#: SIRGT26106WQ-2OMe)

The product SIRGT26106WQ-2OMe is a type of small interfering RNA (siRNA) that targets HSD17B8 gene and regulates the expression of gene. The siRNA interferes with the expression of HSD17B8 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_014234.4
Alternative Names D6S2245E; FABG; FABGL; H2-KE6; HKE6; KE6; RING2; SDR30C1; dJ1033B10.9
Related Diseases Granulomatosis With Polyangiitis
Purification HPLC
Target Gene
Gene ID 7923
Uniprot ID Q92506
Sub Cat Target Species Modification Scale  
SIRGT27106WQ-2F HSD17B8 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28106WQ-2MOE HSD17B8 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29106WQ-LNA HSD17B8 Human Locked Nucleic Acid (LNA) Inquiry

Related Products