siRNA, Anti-HSD3B2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11152WQ-2OMe)

The product SIRGT11152WQ-2OMe is a type of small interfering RNA (siRNA) that targets HSD3B2 gene and regulates the expression of gene. The siRNA interferes with the expression of HSD3B2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000198.3; NM_001166120.1
Alternative Names HSD3B; HSDB; SDR11E2
Related Diseases Adrenal Hyperplasia
Purification HPLC
Target Gene
Gene ID 3284
Uniprot ID P26439
Sub Cat Target Species Modification Scale  
SIRGT12152WQ-2F HSD3B2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13152WQ-2MOE HSD3B2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14152WQ-LNA HSD3B2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11152WQ-RB HSD3B2 Human Ribo-modified Inquiry
SIRGT12152WQ-BB HSD3B2 Human Backbone-modified Inquiry

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