siRNA, Anti-HSPA1B, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT11165WQ-2OMe)

The product SIRGT11165WQ-2OMe is a type of small interfering RNA (siRNA) that targets HSPA1B gene and regulates the expression of gene. The siRNA interferes with the expression of HSPA1B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005346.4
Alternative Names HSP70-1B; HSP70-2; HSP70.2
Related Diseases Mulibrey Nanism, Acute Mountain Sickness
Purification HPLC
Target Gene
Gene ID 3304
Uniprot ID P0DMV9
Sub Cat Target Species Modification Scale  
SIRGT12165WQ-2F HSPA1B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT14165WQ-LNA HSPA1B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11165WQ-RB HSPA1B Human Ribo-modified Inquiry
SIRGT12165WQ-BB HSPA1B Human Backbone-modified Inquiry

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