siRNA, Anti-HTR1D, 2'-F/2'-OMe/2'-MOE/LNA/Ribo-modified(CAT#: SIRGT11189WQ-2OMe)

The product SIRGT11189WQ-2OMe is a type of small interfering RNA (siRNA) that targets HTR1D gene and regulates the expression of gene. The siRNA interferes with the expression of HTR1D gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000864.4
Alternative Names 5-HT1D; HT1DA; HTR1DA; HTRL; RDC4
Related Diseases Migraine With Or Without Aura 1
Purification HPLC
Target Gene
Gene ID 3352
Uniprot ID P28221
Sub Cat Target Species Modification Scale  
SIRGT12189WQ-2F HTR1D Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13189WQ-2MOE HTR1D Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14189WQ-LNA HTR1D Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11189WQ-RB HTR1D Human Ribo-modified Inquiry

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