siRNA, Anti-HTR1E, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11190WQ-2OMe)

The product SIRGT11190WQ-2OMe is a type of small interfering RNA (siRNA) that targets HTR1E gene and regulates the expression of gene. The siRNA interferes with the expression of HTR1E gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000865.2
Alternative Names 5-HT1E
Related Diseases Attention Deficit-Hyperactivity Disorder
Purification HPLC
Target Gene
Gene ID 3354
Uniprot ID P28566
Sub Cat Target Species Modification Scale  
SIRGT12190WQ-2F HTR1E Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13190WQ-2MOE HTR1E Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14190WQ-LNA HTR1E Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11190WQ-RB HTR1E Human Ribo-modified Inquiry
SIRGT12190WQ-BB HTR1E Human Backbone-modified Inquiry

Related Products