siRNA, Anti-HTR5A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11197WQ-2OMe)

The product SIRGT11197WQ-2OMe is a type of small interfering RNA (siRNA) that targets HTR5A gene and regulates the expression of gene. The siRNA interferes with the expression of HTR5A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_024012.3
Alternative Names 5-HT5A
Related Diseases Attention Deficit-Hyperactivity Disorder, Schizophrenia
Purification HPLC
Target Gene
Gene ID 3361
Uniprot ID P47898
Sub Cat Target Species Modification Scale  
SIRGT12197WQ-2F HTR5A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13197WQ-2MOE HTR5A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14197WQ-LNA HTR5A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11197WQ-RB HTR5A Human Ribo-modified Inquiry
SIRGT12197WQ-BB HTR5A Human Backbone-modified Inquiry

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