siRNA, Anti-HUS1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11200WQ-2OMe)

The product SIRGT11200WQ-2OMe is a type of small interfering RNA (siRNA) that targets HUS1 gene and regulates the expression of gene. The siRNA interferes with the expression of HUS1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004507.3
Alternative Names hHUS1
Related Diseases Fanconi Anemia, Complementation Group G
Purification HPLC
Target Gene
Gene ID 3364
Uniprot ID O60921
Sub Cat Target Species Modification Scale  
SIRGT12200WQ-2F HUS1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13200WQ-2MOE HUS1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14200WQ-LNA HUS1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11200WQ-RB HUS1 Human Ribo-modified Inquiry
SIRGT12200WQ-BB HUS1 Human Backbone-modified Inquiry

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