siRNA, Anti-ICAM5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21655WQ-2OMe)

The product SIRGT21655WQ-2OMe is a type of small interfering RNA (siRNA) that targets ICAM5 gene and regulates the expression of gene. The siRNA interferes with the expression of ICAM5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003259.3
Alternative Names TLCN; TLN
Related Diseases Neurodegenerative diseases
Purification HPLC
Target Gene
Gene ID 7087
Uniprot ID Q9UMF0
Sub Cat Target Species Modification Scale  
SIRGT22655WQ-2F ICAM5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23655WQ-2MOE ICAM5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24655WQ-LNA ICAM5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21655WQ-RB ICAM5 Human Ribo-modified Inquiry
SIRGT22655WQ-BB ICAM5 Human Backbone-modified Inquiry

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