siRNA, Anti-IDH3G, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11222WQ-2OMe)
The product SIRGT11222WQ-2OMe is a type of small interfering RNA (siRNA) that targets IDH3G gene and regulates the expression of gene. The siRNA interferes with the expression of IDH3G gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_004135.3; NM_174869.2 |
| Alternative Names | H-IDHG |
| Related Diseases | Inhibited Female Orgasm |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT12222WQ-2F | IDH3G | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT13222WQ-2MOE | IDH3G | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT14222WQ-LNA | IDH3G | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT11222WQ-RB | IDH3G | Human | Ribo-modified | ||
| SIRGT12222WQ-BB | IDH3G | Human | Backbone-modified |