siRNA, Anti-IPP, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT11350WQ-2OMe)

The product SIRGT11350WQ-2OMe is a type of small interfering RNA (siRNA) that targets IPP gene and regulates the expression of gene. The siRNA interferes with the expression of IPP gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001145349.1; NM_005897.2
Alternative Names KLHL27
Related Diseases Retinitis Pigmentosa 46
Purification HPLC
Target Gene
Gene ID 3652
Uniprot ID Q9Y573
Sub Cat Target Species Modification Scale  
SIRGT12350WQ-2F IPP Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13350WQ-2MOE IPP Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT11350WQ-RB IPP Human Ribo-modified Inquiry
SIRGT12350WQ-BB IPP Human Backbone-modified Inquiry

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