siRNA, Anti-IQCA1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46205WQ-2OMe)

The product SIRGT46205WQ-2OMe is a type of small interfering RNA (siRNA) that targets IQCA1 gene and regulates the expression of gene. The siRNA interferes with the expression of IQCA1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001270584.1
Alternative Names 4930465P12Rik; DRC11; IQCA
Related Diseases Primary Ciliary Dyskinesia
Purification HPLC
Target Gene
Gene ID 79781
Uniprot ID Q86XH1
Sub Cat Target Species Modification Scale  
SIRGT47205WQ-2F IQCA1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48205WQ-2MOE IQCA1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49205WQ-LNA IQCA1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46205WQ-RB IQCA1 Human Ribo-modified Inquiry
SIRGT47205WQ-BB IQCA1 Human Backbone-modified Inquiry

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