siRNA, Anti-IQGAP1, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT26599WQ-2OMe)

The product SIRGT26599WQ-2OMe is a type of small interfering RNA (siRNA) that targets IQGAP1 gene and regulates the expression of gene. The siRNA interferes with the expression of IQGAP1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003870.3
Alternative Names HUMORFA01; SAR1; p195
Related Diseases Wolf-Hirschhorn Syndrome
Purification HPLC
Target Gene
Gene ID 8826
Uniprot ID P46940
Sub Cat Target Species Modification Scale  
SIRGT27599WQ-2F IQGAP1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT29599WQ-LNA IQGAP1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26599WQ-RB IQGAP1 Human Ribo-modified Inquiry
SIRGT27599WQ-BB IQGAP1 Human Backbone-modified Inquiry

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