siRNA, Anti-IRAK1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT11351WQ-2OMe)

The product SIRGT11351WQ-2OMe is a type of small interfering RNA (siRNA) that targets IRAK1 gene and regulates the expression of gene. The siRNA interferes with the expression of IRAK1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001025242.1; NM_001025243.1; NM_001569.3
Alternative Names IRAK; pelle
Related Diseases Pediatric Systemic Lupus Erythematosus, Mumps
Purification HPLC
Target Gene
Gene ID 3654
Uniprot ID P51617
Sub Cat Target Species Modification Scale  
SIRGT12351WQ-2F IRAK1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13351WQ-2MOE IRAK1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT11351WQ-RB IRAK1 Human Ribo-modified Inquiry
SIRGT12351WQ-BB IRAK1 Human Backbone-modified Inquiry

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