siRNA, Anti-ITGA5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11371WQ-2OMe)

The product SIRGT11371WQ-2OMe is a type of small interfering RNA (siRNA) that targets ITGA5 gene and regulates the expression of gene. The siRNA interferes with the expression of ITGA5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002205.4
Alternative Names CD49e; FNRA; VLA-5; VLA5A
Related Diseases Intestine Carcinoma In Situ
Purification HPLC
Target Gene
Gene ID 3678
Uniprot ID P08648
Sub Cat Target Species Modification Scale  
SIRGT12371WQ-2F ITGA5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13371WQ-2MOE ITGA5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14371WQ-LNA ITGA5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11371WQ-RB ITGA5 Human Ribo-modified Inquiry
SIRGT12371WQ-BB ITGA5 Human Backbone-modified Inquiry

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