siRNA, Anti-ITGB8, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11388WQ-2OMe)

The product SIRGT11388WQ-2OMe is a type of small interfering RNA (siRNA) that targets ITGB8 gene and regulates the expression of gene. The siRNA interferes with the expression of ITGB8 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002214.2
Related Diseases Hypoplastic Right Heart Syndrome
Purification HPLC
Target Gene
Gene ID 3696
Uniprot ID P26012
Sub Cat Target Species Modification Scale  
SIRGT12388WQ-2F ITGB8 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13388WQ-2MOE ITGB8 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14388WQ-LNA ITGB8 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11388WQ-RB ITGB8 Human Ribo-modified Inquiry
SIRGT12388WQ-BB ITGB8 Human Backbone-modified Inquiry

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