siRNA, Anti-Human JAG1, 2'-OMe(CAT#: SIRGT01121WQ-2OMe)

The product SIRGT01121WQ-2OMe is a type of small interfering RNA (siRNA) that targets JAG1 gene and regulates the expression of gene. The siRNA interferes with the expression of JAG1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification 2ʹ-O-methyl (2'-OMe)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_000214.2
Alternative Names AGS; AGS1; AHD; AWS; CD339; HJ1; JAGL1
Related Diseases Alagille Syndrome 1, Deafness
Purification HPLC
Target Gene
Gene ID 182
Uniprot ID P78504

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