siRNA, Anti-JRK, 2'-OMe-modified(CAT#: SIRGT26446WQ-2OMe)

The product SIRGT26446WQ-2OMe is a type of small interfering RNA (siRNA) that targets JRK gene and regulates the expression of gene. The siRNA interferes with the expression of JRK gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification 2ʹ-O-methyl (2'-OMe)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_001077527.2; NM_001279352.1; NM_003724.3
Alternative Names JH8; jerky
Related Diseases Childhood Absence Epilepsy
Purification HPLC
Target Gene
Gene ID 8629
Uniprot ID O75564

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