siRNA, Anti-KCNA1, 2'-F/2'-OMe/2'-MOE/Ribo-modified(CAT#: SIRGT11416WQ-2OMe)

The product SIRGT11416WQ-2OMe is a type of small interfering RNA (siRNA) that targets KCNA1 gene and regulates the expression of gene. The siRNA interferes with the expression of KCNA1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000217.2
Alternative Names AEMK; EA1; HBK1; HUK1; KV1.1; MBK1; MK1; RBK1
Related Diseases Myokymia with periodic ataxia (AEMK)
Purification HPLC
Target Gene
Gene ID 3736
Uniprot ID Q09470
Sub Cat Target Species Modification Scale  
SIRGT12416WQ-2F KCNA1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13416WQ-2MOE KCNA1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT11416WQ-RB KCNA1 Human Ribo-modified Inquiry

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