siRNA, Anti-KCNAB3, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT26851WQ-2OMe)

The product SIRGT26851WQ-2OMe is a type of small interfering RNA (siRNA) that targets KCNAB3 gene and regulates the expression of gene. The siRNA interferes with the expression of KCNAB3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004732.3
Alternative Names AKR6A9; KCNA3.1B; KCNA3B; KV-BETA-3
Related Diseases Cone-Rod Dystrophy 6
Purification HPLC
Target Gene
Gene ID 9196
Uniprot ID O43448
Sub Cat Target Species Modification Scale  
SIRGT27851WQ-2F KCNAB3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28851WQ-2MOE KCNAB3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT26851WQ-RB KCNAB3 Human Ribo-modified Inquiry
SIRGT27851WQ-BB KCNAB3 Human Backbone-modified Inquiry

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