siRNA, Anti-KDSR, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06619WQ-2OMe)

The product SIRGT06619WQ-2OMe is a type of small interfering RNA (siRNA) that targets KDSR gene and regulates the expression of gene. The siRNA interferes with the expression of KDSR gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002035.2
Alternative Names DHSR; EKVP4; FVT1; SDR35C1
Related Diseases Spinal muscular atrophy
Purification HPLC
Target Gene
Gene ID 2531
Uniprot ID Q06136
Sub Cat Target Species Modification Scale  
SIRGT07619WQ-2F KDSR Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08619WQ-2MOE KDSR Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09619WQ-LNA KDSR Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06619WQ-RB KDSR Human Ribo-modified Inquiry
SIRGT07619WQ-BB KDSR Human Backbone-modified Inquiry

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