siRNA, Anti-KIAA0319L, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46322WQ-2OMe)

The product SIRGT46322WQ-2OMe is a type of small interfering RNA (siRNA) that targets KIAA0319L gene and regulates the expression of gene. The siRNA interferes with the expression of KIAA0319L gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_024874.4
Alternative Names AAVR; AAVRL
Related Diseases Limited Scleroderma and Dyslexia
Purification HPLC
Target Gene
Gene ID 79932
Uniprot ID Q8IZA0
Sub Cat Target Species Modification Scale  
SIRGT47322WQ-2F KIAA0319L Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48322WQ-2MOE KIAA0319L Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49322WQ-LNA KIAA0319L Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46322WQ-RB KIAA0319L Human Ribo-modified Inquiry
SIRGT47322WQ-BB KIAA0319L Human Backbone-modified Inquiry

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