siRNA, Anti-KIAA0586, 2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31292WQ-2OMe)
The product SIRGT31292WQ-2OMe is a type of small interfering RNA (siRNA) that targets KIAA0586 gene and regulates the expression of gene. The siRNA interferes with the expression of KIAA0586 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001244189.1; NM_001244190.1; NM_001244191.1; NM_001244192.1; NM_001244193.1; NM_001329943.1; NM_001329944.1; NM_001329945.1; NM_001329946.1; NM_001329947.1; NM_014749.4 |
| Alternative Names | JBTS23; SRTD14; Talpid3 |
| Related Diseases | Short-Rib Thoracic Dysplasia 14 With Polydactyly |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT33292WQ-2MOE | KIAA0586 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT34292WQ-LNA | KIAA0586 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT31292WQ-RB | KIAA0586 | Human | Ribo-modified | ||
| SIRGT32292WQ-BB | KIAA0586 | Human | Backbone-modified |
