siRNA, Anti-KIF3B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26966WQ-2OMe)

The product SIRGT26966WQ-2OMe is a type of small interfering RNA (siRNA) that targets KIF3B gene and regulates the expression of gene. The siRNA interferes with the expression of KIF3B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004798.3
Alternative Names FLA8; HH0048; KLP-11
Related Diseases Myasthenic Syndrome, Congenital, 16
Purification HPLC
Target Gene
Gene ID 9371
Uniprot ID O15066
Sub Cat Target Species Modification Scale  
SIRGT27966WQ-2F KIF3B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28966WQ-2MOE KIF3B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29966WQ-LNA KIF3B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26966WQ-RB KIF3B Human Ribo-modified Inquiry
SIRGT27966WQ-BB KIF3B Human Backbone-modified Inquiry

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