siRNA, Anti-KISS1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11474WQ-2OMe)

The product SIRGT11474WQ-2OMe is a type of small interfering RNA (siRNA) that targets KISS1 gene and regulates the expression of gene. The siRNA interferes with the expression of KISS1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002256.3
Alternative Names HH13; KiSS-1
Related Diseases Normosmic Congenital Hypogonadotropic Hypogonadism
Purification HPLC
Target Gene
Gene ID 3814
Uniprot ID Q15726
Sub Cat Target Species Modification Scale  
SIRGT12474WQ-2F KISS1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13474WQ-2MOE KISS1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14474WQ-LNA KISS1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11474WQ-RB KISS1 Human Ribo-modified Inquiry
SIRGT12474WQ-BB KISS1 Human Backbone-modified Inquiry

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