siRNA, Anti-KLHL24, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41288WQ-2OMe)

The product SIRGT41288WQ-2OMe is a type of small interfering RNA (siRNA) that targets KLHL24 gene and regulates the expression of gene. The siRNA interferes with the expression of KLHL24 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001349413.1
Alternative Names DRE1; EBSSH; KRIP6
Related Diseases Epidermolysis Bullosa Simplex, Generalized
Purification HPLC
Target Gene
Gene ID 54800
Uniprot ID Q6TFL4
Sub Cat Target Species Modification Scale  
SIRGT42288WQ-2F KLHL24 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43288WQ-2MOE KLHL24 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44288WQ-LNA KLHL24 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41288WQ-RB KLHL24 Human Ribo-modified Inquiry
SIRGT42288WQ-BB KLHL24 Human Backbone-modified Inquiry

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