siRNA, Anti-KLK15, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41738WQ-2OMe)

The product SIRGT41738WQ-2OMe is a type of small interfering RNA (siRNA) that targets KLK15 gene and regulates the expression of gene. The siRNA interferes with the expression of KLK15 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001277081.1
Alternative Names ACO; HSRNASPH
Related Diseases Peripheral Vascular Disease
Purification HPLC
Target Gene
Gene ID 55554
Uniprot ID Q9H2R5
Sub Cat Target Species Modification Scale  
SIRGT42738WQ-2F KLK15 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43738WQ-2MOE KLK15 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44738WQ-LNA KLK15 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41738WQ-RB KLK15 Human Ribo-modified Inquiry
SIRGT42738WQ-BB KLK15 Human Backbone-modified Inquiry

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