siRNA, Anti-KMT2A, 2'-F/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT13793WQ-2MOE)
The product SIRGT13793WQ-2MOE is a type of small interfering RNA (siRNA) that targets KMT2A gene and regulates the expression of gene. The siRNA interferes with the expression of KMT2A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001197104.1; NM_005933.3 |
| Alternative Names | ALL-1; CXXC7; HRX; HTRX1; MLL; MLL1; MLL1A; TRX1; WDSTS |
| Related Diseases | Wiedemann-Steiner Syndrome |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT14793WQ-LNA | KMT2A | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT92342WQ-2F | Kmt2a | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT93342WQ-2MOE | Kmt2a | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT94342WQ-LNA | Kmt2a | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT11793WQ-RB | KMT2A | Human | Ribo-modified | ||
| SIRGT91342WQ-RB | Kmt2a | Mouse | Ribo-modified | ||
| SIRGT92342WQ-BB | Kmt2a | Mouse | Backbone-modified |
