siRNA, Anti-KNG1, 2'-F/2'-OMe/LNA/Ribo-modified(CAT#: SIRGT11484WQ-2OMe)

The product SIRGT11484WQ-2OMe is a type of small interfering RNA (siRNA) that targets KNG1 gene and regulates the expression of gene. The siRNA interferes with the expression of KNG1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000893.3; NM_001102416.2; NM_001166451.1
Alternative Names BDK; BK; KNG
Related Diseases High Molecular Weight Kininogen Deficiency
Purification HPLC
Target Gene
Gene ID 3827
Uniprot ID P01042
Sub Cat Target Species Modification Scale  
SIRGT12484WQ-2F KNG1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT14484WQ-LNA KNG1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11484WQ-RB KNG1 Human Ribo-modified Inquiry

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