siRNA, Anti-KREMEN1, 2'-F/2'-OMe/2'-MOE/LNA/Backbone-modified(CAT#: SIRGT46741WQ-2OMe)

The product SIRGT46741WQ-2OMe is a type of small interfering RNA (siRNA) that targets KREMEN1 gene and regulates the expression of gene. The siRNA interferes with the expression of KREMEN1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001039570.2
Alternative Names ECTD13; KREMEN; KRM1
Related Diseases Hand, Foot And Mouth Disease
Purification HPLC
Target Gene
Gene ID 83999
Uniprot ID Q96MU8
Sub Cat Target Species Modification Scale  
SIRGT47741WQ-2F KREMEN1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48741WQ-2MOE KREMEN1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49741WQ-LNA KREMEN1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT47741WQ-BB KREMEN1 Human Backbone-modified Inquiry

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