siRNA, Anti-KRT14, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11513WQ-2OMe)

The product SIRGT11513WQ-2OMe is a type of small interfering RNA (siRNA) that targets KRT14 gene and regulates the expression of gene. The siRNA interferes with the expression of KRT14 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000526.4
Alternative Names CK14; EBS3; EBS4; K14; NFJ
Related Diseases Epidermolysis Bullosa Simplex
Purification HPLC
Target Gene
Gene ID 3861
Uniprot ID P02533
Sub Cat Target Species Modification Scale  
SIRGT12513WQ-2F KRT14 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13513WQ-2MOE KRT14 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14513WQ-LNA KRT14 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11513WQ-RB KRT14 Human Ribo-modified Inquiry
SIRGT12513WQ-BB KRT14 Human Backbone-modified Inquiry

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