siRNA, Anti-KRT33A, 2'-OMe/2'-MOE/LNA/Ribo-modified(CAT#: SIRGT11521WQ-2OMe)

The product SIRGT11521WQ-2OMe is a type of small interfering RNA (siRNA) that targets KRT33A gene and regulates the expression of gene. The siRNA interferes with the expression of KRT33A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004138.3
Alternative Names HA3I; Ha-3I; K33A; KRTHA3A; Krt1-3; hHa3-I
Related Diseases Epidermolytic Hyperkeratosis
Purification HPLC
Target Gene
Gene ID 3883
Uniprot ID O76009
Sub Cat Target Species Modification Scale  
SIRGT13521WQ-2MOE KRT33A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14521WQ-LNA KRT33A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11521WQ-RB KRT33A Human Ribo-modified Inquiry

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