siRNA, Anti-KRT4, 2'-F/2'-OMe/Ribo/Backbone-modified(CAT#: SIRGT11503WQ-2OMe)

The product SIRGT11503WQ-2OMe is a type of small interfering RNA (siRNA) that targets KRT4 gene and regulates the expression of gene. The siRNA interferes with the expression of KRT4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002272.3
Alternative Names CK-4; CK4; CYK4; K4; WSN1
Related Diseases White Sponge Nevus, Leukoplakia
Purification HPLC
Target Gene
Gene ID 3851
Uniprot ID P19013
Sub Cat Target Species Modification Scale  
SIRGT12503WQ-2F KRT4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT11503WQ-RB KRT4 Human Ribo-modified Inquiry
SIRGT12503WQ-BB KRT4 Human Backbone-modified Inquiry

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