siRNA, Anti-KRTAP17-1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46716WQ-2OMe)
The product SIRGT46716WQ-2OMe is a type of small interfering RNA (siRNA) that targets KRTAP17-1 gene and regulates the expression of gene. The siRNA interferes with the expression of KRTAP17-1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_031964.1 |
| Alternative Names | KAP17.1; KRTAP16.1; KRTAP17.1 |
| Related Diseases | Limited Scleroderma |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT47716WQ-2F | KRTAP17-1 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT48716WQ-2MOE | KRTAP17-1 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT49716WQ-LNA | KRTAP17-1 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT46716WQ-RB | KRTAP17-1 | Human | Ribo-modified | ||
| SIRGT47716WQ-BB | KRTAP17-1 | Human | Backbone-modified |
