siRNA, Anti-LAMP1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT11545WQ-2OMe)

The product SIRGT11545WQ-2OMe is a type of small interfering RNA (siRNA) that targets LAMP1 gene and regulates the expression of gene. The siRNA interferes with the expression of LAMP1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005561.3
Alternative Names CD107a; LAMPA; LGP120
Related Diseases Chediak-Higashi Syndrome, Salla Disease
Purification HPLC
Target Gene
Gene ID 3916
Uniprot ID P11279
Sub Cat Target Species Modification Scale  
SIRGT12545WQ-2F LAMP1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13545WQ-2MOE LAMP1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT11545WQ-RB LAMP1 Human Ribo-modified Inquiry
SIRGT12545WQ-BB LAMP1 Human Backbone-modified Inquiry

Related Products